Medición de Ca2+ intraceIuar, Patch clamp. Pletismografía. órganos aislados.

Western blot e inmunofluorescencia

PERSONAL:

Dr. Luis Manuel Montaño Ramírez
Profesor Titular

Dr. Jorge Eduardo Reyes García
Profesor Asociado

Dra. Abril Carbajal García
Profesor Asociado

María del Pilar González Romo
Jefa de Laboratorio

ESTUDIANTES DE POSGRADO:

Bianca S Romero Martínez
Doctorado en Ciencias Biomédicas

María F Casas Hernández
Maestría en Ciencias de la Salud

1. Romero-Martínez BS, Sommer B, Solís-Chagoyán H, Calixto E, Aquino-Gálvez A, Jaimez R, Gomez-Verjan JC, González-Avila G, Flores-Soto E, Montaño LM. Estrogenic Modulation of Ionic Channels, Pumps and Exchangers in Airway Smooth Muscle. Int. J. Mol. Sci. (ISSN 1422-0067), accepted on 28 February 2023. FI: 6.208
2. Reyes-García J, Díaz-Hernández V, Carbajal-García A, Casa-Hernández MF, Sommer B, Montaño LM. Theophylline-Induced Relaxation is Enhanced after Testosterone Treatment via Increased KV1.2 and KV1.5 Protein Expression in Guinea Pig Tracheal Smooth Muscle. Int. J. Mol. Sci. (ISSN 1422-0067), 2023, 24, 5884. Doi.org/10.3390/ ijms24065884. FI: 6.208
3. Díaz-Hernández V, Montaño LM, Caldelas I, Marmolejo-Valencia A. A high-fat and high-carbohydrate diet promotes reminiscent hallmarks of an aging ovary in the rabbit model. Biomedicines, 2022, 10, 3068. Doi.org/10.3390/biomedicines10123068. FI:
4. Montaño LM, Sommer B, Gomez-Verjan JC, Morales-Paoli GS, Ramírez-Salinas GL, Solís-Chagoyán H, Sanchez-Florentino ZA, Calixto E, Pérez-Figueroa GE, Carter R, Jaimez-Melgoza R, Romero-Martínez BS, Flores-Soto E. Theophylline: Old drug in a new light, application in COVID-19 through computational studies. Int J Mol Sci., 2022, 23, 4167. Doi.org/10.3390/ijms23084167. FI: 6.208
5. Montaño LM, Sommer B, Solís-Chagoyán, Romero-Martínez BS, Aquino-Gálvez A, Gomez-Verjan JC, Calixto E, González-Avila G, Flores-Soto E. Could Lower Testosterone in Older Men Explain Higher COVID-19 Morbidity and Mortalities? Int J Mol Sci., 2022, 23, 935. Doi.org/10.3390/ijms23020935. FI: 6.208
6. Reyes-García J, Carbajal-García A, Montaño LM. Transient receptor potential cation channel subfamily V (TRPV) and its importance in asthma. Eur J Pharmacol., 915, 2022 174692. Doi.org/10.1016/j.ejphar.2021.174692. FI: 5.195
7. Romero-Martínez BS, Montaño LM, Solís-Chagoyán H, Sommer B, Ramírez-Salinas GL, Pérez-Figueroa GE, Flores-Soto E. Possible Beneficial Actions of Caffeine in SARS-CoV-2. Int J Mol Sci. 22(11):5460, 2021. Doi: 10.3390/ijms22115460. FI: 6.208
8. Carbajal-García A, Reyes-García J, Montaño LM. Androgen effects on the adrenergic system of the vascular, airway, and cardiac myocytes and their relevance in pathological processes. Int J Endocrinol, 2020: 8849641, 25 pages, 2020. Doi.org/10.1155/2020/8849641. FI: 2.759
9. Vargas-Martínez EM, Gómez-Coronado KS, Espinosa-Luna R, Valdez-Morales EE, Barrios-Garcia T, Barajas-Espinosa A, Ochoa-Cortes F, Montaño LM, Barajas-López C, Guerrero-Alba R. Functional expression of P2X1, P2X4 and P2X7 purinergic receptors in human monocyte-derived macrophages. Eur J Pharmacol, 888, 173460, 2020. doi: 10.1016/j.ejphar.2020.173460. FI: 5.195
10. Carbajal-García A, Reyes-García J, Casas-Hernández MF, Flores-Soto E, Díaz-Hernández V, Sommer B, Montaño LM. Testosterone augments β2 adrenergic receptor genomic transcription increasing salbutamol relaxation in airway smooth muscle. Molecular and Cellular Endocrinology, 510:110801, 2020. doi: 10.1016/j.mce.2020.110801
11. Montaño LM, Flores-Soto E, Sommer B, Solís-Chagoyán H, Perusquía M. Androgens are effective bronchodilators with anti-inflammatory properties: A potential alternative for asthma therapy. Steroids, 153:108509, 2020. Doi: 10.1016/j.steroids.2019.108509
12. Montaño LM, Flores-Soto E. Respuesta a: “COVID-19 y su asociación con los IECA y ARAII” Revista de la Facultad de Medicina de la UNAM, 63(6): 55-57, 2020. Doi: 10.22201/fm.24484865e.2020.63.6.08
13. Montaño LM, Flores-Soto E. COVID-19 y su asociación con los inhibidores de la enzima convertidora de angiotensina y los antagonistas de los receptores para angiotensina II. Revista de la Facultad de Medicina de la UNAM, 63(4): 30-34, 2020. Doi.org/10.22201/fm.24484865e.2020.63.4.05
14. Solís-Chagoyán H, Flores-Soto E, Valdés-Tobar M, Cercós MG, Calixto E, Montaño LM, Barájas-López C, Sommer B, Aquino-Gálvez A, Trueta C, Benítez-King G. Purinergic Signaling Pathway in Human Olfactory Neuronal Precursor Cells. Steam cells International, Article ID 2728786, 17, 2019. Doi.org/10.1155/2019/2728786
15. Díaz-Hernández V, Caldelas I, Montaño LM, Merchant-Larios H. Morphological rearrangement of the cortical region, in aging ovaries. Histology and Histopathology, 34(7): 775-789, 2019. Doi: 10.14670/HH-18-078.
16. Wang Y-X, Reyes-García J, Di Mise A, and Zheng Y-M. Role of ryanodine receptor 2 and FK506-bindingprotein 12.6 dissociation in pulmonary hypertension. Journal of General Physiology. 2022. 155:3. doi.org/10.1085/jgp.202213100.
17. Reyes-García J, Carbajal-García A, Di Mise A, Zheng Y-M, Wang X, and Wang Y-X. Important functions and Molecular Mechanisms of Mitochondrial Redox Signaling in Pulmonary Hypertension. Antioxidants. 2022. 11, 473. doi: 10.3390/antiox11030473.
18. Li XQ, Zheng YM, Reyes-García J, Wang YX. Diversity of ryanodine receptor 1-mediated Ca2+ signaling in systemic and pulmonary artery smooth muscle cells. Life Sci. 2021. 1;270:119016. doi: 10.1016/j.lfs.2021.119016.
19. Tang Q, Zheng YM, Song T, Reyes-García J, Wang C, Wang YX. Inhibition of big-conductance Ca2+-activated K+ channels in cerebral artery (vascular) smooth muscle cells is a major novel mechanism for tacrolimus-induced hypertension. Pflugers Arch. 2021; (1):53-66. doi: 10.1007/s00424-020-02470-6.
20. Reyes-García J, Montaño LM, Carbajal-García A, Wang YX. Sex hormones and lung inflammation. Adv Exp Med Biol. 2021;1304:259-321. doi: 10.1007/978-3-030-68748-9_15. ISBN: 978-303-68747-2.
21. Maietta V, Reyes-García J*, Yadav VR, Zheng YM, Peng X, Wang YX. Cellular and Molecular Processes in Pulmonary Hypertension. Adv Exp Med Biol. 2021;1304:21-38. doi: 10.1007/978-3-030-68748-9_2. ISBN: 978-303-68747-2.
22. Yang Z, Song T, Truong L, Reyes-García J, Wang L, Zheng YM, Wang YX Important Role of Sarcoplasmic Reticulum Ca2+ Release via Ryanodine Receptor-2 Channel in Hypoxia-Induced Rieske Iron-Sulfur Protein-Mediated Mitochondrial Reactive Oxygen Species Generation in Pulmonary Artery Smooth Muscle Cells. Antioxid Redox Signal. 2020 Mar 1;32(7):447-462. doi: 10.1089/ars.2018.7652. Epub 2019. Factor de impacto 6.323. Número de citas: 10.
23. Flores-Soto E, Romero-Martínez BS, Solís-Chagoyán H, Estrella-Parra EA, Avila-Acevedo JG, Gomez-Verjan JC, Reyes-García J, Casas-Hernández MF, Sommer B, Montaño LM. Chamaecyparis lawsoniana and Its Active Compound Quercetin as Ca2+ Inhibitors in the Contraction of Airway Smooth Muscle. Molecules. 2024 May 12;29(10):2284. doi: 10.3390/molecules29102284. PMID: 38792145; PMCID: PMC11123793.
24. Romero-Martínez BS, Flores-Soto E, Sommer B, Reyes-García J, Arredondo-Zamarripa D, Solís-Chagoyán H, Lemini C, Rivero-Segura NA, Santiago-de-la-Cruz JA, Pérez-Plascencia C, Montaño LM. 17β-estradiol induces hyperresponsiveness in guinea pig airway smooth muscle by inhibiting the plasma membrane Ca2+-ATPase. Mol Cell Endocrinol. 2024 Sep 1;590:112273. doi: 10.1016/j.mce.2024.112273. Epub 2024 May 18. PMID: 38763427.
25. Carbajal-García A, Reyes-García J, Díaz-Hernández V, Casas-Hernández MF, Flores-Murrieta FJ, Montaño LM. Testosterone Enhances Kv Currents and Airway Smooth Muscle Relaxation Induced by ATP and UTP through P2Y4 Receptors and Adenylyl Cyclase Pathway. Int J Mol Sci. 2024 Apr 24;25(9):4652. doi: 10.3390/ijms25094652. PMID: 38731872; PMCID: PMC11083821.
26. Montaño LM, Carbajal-García A, Casas-Hernández MF, Arredondo-Zamarripa D, Reyes-García J. TRPV4 Activation during Guinea Pig Airway Smooth Muscle Contraction Promotes Ca2+ and Na+ Influx. Pharmaceuticals (Basel). 2024 Feb 24;17(3):293. doi: 10.3390/ph17030293. PMID: 38543079; PMCID: PMC10976253.